Neural Tube Defects and Spina Bifida

What are neural tube defects or NTDs?

In the United States, neural tube defects are one of the most common birth defects, happening to approximately one in 1,000 live births. An NTD is an opening in the spinal cord or brain that occurs early on, sometimes so early that the mother doesn't even know she is pregnant yet.

There are two types of neural tube defects: 1) open which is more common, and 2) closed. Open neural tube defects happen when the brain and/or spinal cord are exposed at birth through a defect in the skull or back bone. The more common open defects are spina bifida and anencephaly.

Spina bifida is the most common type of NTD. According to the National Institute of Neurological Disorders and Stroke (NINDS), spina bifida affects about 1,500 to 2,000 babies born in the United States each year. About 80% of those affected will have normal intelligence, according to the Spina Bifida Association, but some will have learning disabilities. Physical complications may include hydrocephalus, a condition where fluid accumulates in the brain, enlarging the head and sometimes causes brain damage; gastrointestinal disorders, urinary and bowel dysfunction, obesity, depression, tendonitis, and tendency towards latex allergies.

What causes neural tube defects?

The cause is not readily known. Some causes allude to genetic, environmental, and nutritional or folic acid deficiencies. According to the March of Dimes, about 95% of babies born with neural tube defects have no family history of NTDs. Some seizure medications, such as valproic acid (brand Depakote) are associated with an increased risk as well as maternal diabetes, radiation, and cigarettes.

According to the Centers for Disease Control, women who are pregnant, or thinking about becoming pregnant, should know there are risks associated with using prescription painkillers. One of the risks is spina bifida.

What's the treatment for neural tube defects?

Treatment depends on severity. An aggressive surgical approach has improved survival and functions of infants with spina bifida; the success of surgery depends on the amount of brain tissue involved.

The goal is to permit the person with neural tube defects to achieve the highest level of functionality and independence.

Does your child suffer from NTDs caused by taking the anti seizure medication Depakote?

Did your child suffer from anencephaly after you were prescribed Depakote while pregnant?

Do you have a neural tube defect lawsuit?

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